Reduction of circulating 2-microglobulin level for the treatment of dialysis-related amyloidosis
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چکیده
منابع مشابه
Reduction of circulating beta2-microglobulin level for the treatment of dialysis-related amyloidosis.
Dialysis-related amyloidosis (DRA) is a common complication associated with long-term haemodialysis therapy. The elimination of beta2-microglobulin (beta2m), the major constituent of the amyloid fibrils in DRA, from circulation has been expected to bring some clinical benefit. Recently, a direct haemoperfusion method using selective beta2m absorption column to eliminate circulating beta2m has b...
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Lixelle is a direct hemoperfusion-type adsorption column that was developed to selectively eliminate beta2-microglobulin (beta2-m) from the circulating blood of patients with dialysis-related amyloidosis (DRA). The adsorbent in Lixelle comprises porous cellulose beads to which hydrophobic hexadecyl alkyl chain is covalently bound. One milliliter of wet Lixelle beads eliminates more than 1 mg of...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2001
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/16.suppl_4.31